This study was an initial investigation on the kinds of signature pedagogies employed in the Information Systems discipline. It attempted to identify the most frequently used instructional strategies to teach in the information systems discipline. This study employed an exploratory study design, through a U.S. national survey. A link to a web-based survey was sent by email to all information systems faculty members who were listed in the Association of Information Systems membership directory on the web, filtered only to those faculty members in the United States. This study managed to secure 695 valid responses obtained from 2,835 eligible participants (24.4% response rate). The data were analyzed with descriptive statistics and factors analysis to group the instructional strategies into similar groups. The results show that lecture-based instructional strategies remain the dominant in the information systems discipline, with over 66% participants identified lecture as the most frequently used strategy when teaching in the classroom. Two out of six groups identified by Exploratory Factor Analysis (EFA) method had higher means in the frequency of use, the project-based strategies and the highly-structured active learning strategies.