MobileSchool model is developed for the implementation of MobileSchool system in Malaysian secondary schools. This paper presents practitioners’ perceptions on effectiveness of MobileSchool model. For this specific study, practitioners refer to practitioners in field of information and communication technology (ICT) and education. This study uses questionnaire instrument that involves 108 respondents who are in ICT and education fields. MobileSchool model involves five variables; software as a service (SaaS) of cloud computing, mobile web technology, transactional distance theory (TDT), Social Information Processing theory (SIPT) and mobile usability principle. Descriptive analysis and hypothesis evaluation have been conducted to validate the effectiveness of the variables that were included in MobileSchool model. Five hypotheses have been constructed to represent five variables. In analyzing the data, Pearson’s Product-Moment Correlation has been conducted to determine significant correlation between these five variables with the effectiveness of MobileSchool model. Results showed that the mean score of all variables were higher than mean of Likert scale, thus, most of the respondents gave positive feedbacks to all elements identified in MobileSchool model. Besides, result also showed that there are statistical evidence to proof the significant relationship between variables of MobileSchool model and the effectiveness of MobileSchool model to be implemented in MobileSchool system.